Looking deeper on the Greeks to help vet trades like this?

I'm using a custom scan that is an aggregate of several indicators that triggers under certain conditions for a positive or negative confluence.

Been at this a while, catch a few but never enough position size for long enough. Issue is the scan has about 80% false positives and 20% solid moves.

I'm trying to refine the scan results so that it tosses out the duds and focuses more on the winners. Good experience with trading but options not as much.

When a stock like $BA has good news like they did this morning plus a conference at SB, what could it be about the Greeks that allows the option to really move like it did here up +2,400%? Is it gamma profiles? Relative volume on the Open Interest? Anything else you would use as an experienced options trader to cull out the winners?

\[ I realize the probability curves on a strike several handles away from OTM are risky \]